Microbubbles coupled to methotrexate-loaded liposomes for ultrasound-mediated delivery of methotrexate across the blood–brain barrier

Methotrexate (MTX) is the single most effective agent for the treatment of primary central nervous system lymphoma. Currently, the delivery of MTX to the brain is achieved by high systemic doses, which cause severe long-term neurotoxicity, or intrathecal administration, which is highly invasive and...

詳細記述

保存先:
書誌詳細
主要な著者: Wang, Xiang, Liu, Ping, Yang, Weixiao, Li, Lu, Li, Peijing, Liu, Zheng, Zhuo, Zhongxiong, Gao, Yunhua
フォーマット: Artigo
言語:Inglês
出版事項: Dove Medical Press 2014
主題:
Original Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211917/
https://ncbi.nlm.nih.gov/pubmed/25364248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S69845
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