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Two Clinical Phenotypes in Polycythemia Vera

BACKGROUND: Polycythemia vera is the ultimate phenotypic consequence of the V617F mutation in Janus kinase 2 (encoded by JAK2), but the extent to which this mutation influences the behavior of the involved CD34+ hematopoietic stem cells is unknown. METHODS: We analyzed gene expression in CD34+ perip...

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Autors principals: Spivak, Jerry L., Considine, Michael, Williams, Donna M., Talbot, Conover C., Rogers, Ophelia, Moliterno, Alison R., Jie, Chunfa, Ochs, Michael F.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211877/
https://ncbi.nlm.nih.gov/pubmed/25162887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1403141
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