Disruption of the ASXL1 gene is frequent in primary, post-essential thrombocytosis and post-polycythemia vera myelofibrosis, but not essential thrombocytosis or polycythemia vera: analysis of molecular genetics and clinical phenotypes

BACKGROUND: The myeloproliferative neoplasms, essential thrombocytosis, polycythemia vera and primary myelofibrosis, share the same acquired genetic lesion, but the concept of JAK2 V617F serving as the sole lesion responsible for these neoplasms is under question, and there has been interest in iden...

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Detalhes bibliográficos
Main Authors: Stein, Brady L., Williams, Donna M., O’Keefe, Christine, Rogers, Ophelia, Ingersoll, Roxann G., Spivak, Jerry L., Verma, Amit, Maciejewski, Jarek P., McDevitt, Michael A., Moliterno, Alison R.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2011
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186307/
https://ncbi.nlm.nih.gov/pubmed/21712540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.045591
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