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Inhibition of Mus81 by siRNA enhances sensitivity to 5-FU in breast carcinoma cell lines

PURPOSE: One of the most challenging aspects of breast carcinoma chemotherapy is the rapid acquirement of drug resistance. Improving the sensitivity to chemotherapeutic drugs is very important for successful treatment. Mus81 plays an important role in maintaining the stability of the genome and DNA...

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Main Authors: Qian, Ying, Liu, Yanning, Yan, Qiuyue, Lv, Juan, Ni, Xiaoyan, Wu, Yunlu, Dong, Xuejun
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4211853/
https://ncbi.nlm.nih.gov/pubmed/25364260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S64339
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