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Closing in on a mechanism for activation

When insulin-like growth factor-1 (IGF1) binds to its receptor, a physical constraint is released that allows the two transmembrane helices to come together to facilitate activation of the receptor.

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hubbard, Stevan R, Miller, W Todd
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210822/
https://ncbi.nlm.nih.gov/pubmed/25350976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04909
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