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Closing in on a mechanism for activation
When insulin-like growth factor-1 (IGF1) binds to its receptor, a physical constraint is released that allows the two transmembrane helices to come together to facilitate activation of the receptor.
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
eLife Sciences Publications, Ltd
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4210822/ https://ncbi.nlm.nih.gov/pubmed/25350976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04909 |
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