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Receptor tyrosine kinases: mechanisms of activation and signaling

Receptor tyrosine kinases (RTKs) are essential components of signal transduction pathways that mediate cell-to-cell communication. These single-pass transmembrane receptors, which bind polypeptide ligands — mainly growth factors — play key roles in processes such as cellular growth, differentiation,...

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Bibliografiske detaljer
Main Authors: Hubbard, Stevan R., Miller, W. Todd
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536775/
https://ncbi.nlm.nih.gov/pubmed/17306972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2007.02.010
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