Identification of gene regulation patterns underlying both E(2)- and tamoxifen-stimulated cell growth through global gene expression profiling in breast cancer cells

PURPOSE: A c-Src inhibitor blocks estrogen (E(2))-induced stress and converts E(2) responses from inducing apoptosis to growth stimulation in E(2)-deprived breast cancer cells. A reprogrammed cell line, MCF-7:PF, results in a functional estrogen receptor (ER). We addressed the question of whether th...

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Main Authors: Fan, Ping, Cunliffe, Heather E., Griffith, Obi L., Agboke, Fadeke A., Ramos, Pilar, Gray, Joe W., Jordan, V. Craig
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210771/
https://ncbi.nlm.nih.gov/pubmed/25212499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2014.08.010
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