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Inhibition of c-Src Blocks Estrogen-induced Apoptosis and Restores Estrogen-Stimulated Growth in Long-term Estrogen-Deprived Breast Cancer Cells
PURPOSE: Our publications demonstrate that physiological concentrations of estrogen (E(2)) induce endoplasmic reticulum and oxidative stress which finally result in apoptosis in E(2)-deprived breast cancer cells, MCF-7:5C. c-Src is involved in the process of E(2)-induced stress. To mimic the clinica...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947251/ https://ncbi.nlm.nih.gov/pubmed/24183378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2013.10.001 |
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