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The Evolution of Nonsteroidal Antiestrogens to become Selective Estrogen Receptor Modulators

The discovery of the first nonsteroidal antiestrogen ethamoxytriphetol (MER25) in 1958, opened the door to a wide range of clinical applications. However, the finding that ethamoxytriphetol was a “morning after” pill in laboratory animals, energized the pharmaceutical industry to discover more poten...

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Detalhes bibliográficos
Main Authors: Jordan, V. Craig, McDaniel, Russell, Agboke, Fadeke, Maximov, Philipp Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192084/
https://ncbi.nlm.nih.gov/pubmed/24949934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2014.06.009
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