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A molecular model for the mechanism of acquired tamoxifen resistance in breast cancer
PURPOSE: Estrogen (E(2))-stimulated growth re-emerges after a c-Src inhibitor blocking E(2)-induced apoptosis. A resulting cell line, MCF-7:PF, is selected with features of functional estrogen receptor (ER) and over-expression of insulin-like growth factor-1 receptor beta (IGF-1Rβ). We addressed the...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4194144/ https://ncbi.nlm.nih.gov/pubmed/25204804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2014.08.011 |
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