Pharmacological Inhibition of Dynamin II Reduces Constitutive Protein Secretion from Primary Human Macrophages

Dynamins are fission proteins that mediate endocytic and exocytic membrane events and are pharmacological therapeutic targets. These studies investigate whether dynamin II regulates constitutive protein secretion and show for the first time that pharmacological inhibition of dynamin decreases secret...

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Autors principals: Kockx, Maaike, Karunakaran, Denuja, Traini, Mathew, Xue, Jing, Huang, Kuan Yen, Nawara, Diana, Gaus, Katharina, Jessup, Wendy, Robinson, Phillip J., Kritharides, Leonard
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210248/
https://ncbi.nlm.nih.gov/pubmed/25347775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111186
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