Glycosylation and Sialylation of Macrophage-derived Human Apolipoprotein E Analyzed by SDS-PAGE and Mass Spectrometry: EVIDENCE FOR A NOVEL SITE OF GLYCOSYLATION ON SER(290)

Apolipoprotein E (apoE) is a 34-kDa glycoprotein secreted from various cells including hepatocytes and macrophages and plays an important role in remnant lipoprotein clearance, immune responses, Alzheimer disease, and atherosclerosis. Cellular apoE and plasma apoE exist as multiple glycosylated and...

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Main Authors: Lee, Youra, Kockx, Maaike, Raftery, Mark J., Jessup, Wendy, Griffith, Renate, Kritharides, Leonard
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2010
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938105/
https://ncbi.nlm.nih.gov/pubmed/20511397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M900430-MCP200
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