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A Novel In Vitro Method for Detecting Undifferentiated Human Pluripotent Stem Cells as Impurities in Cell Therapy Products Using a Highly Efficient Culture System

Innovative applications of cell therapy products (CTPs) derived from human pluripotent stem cells (hPSCs) in regenerative medicine are currently being developed. The presence of residual undifferentiated hPSCs in CTPs is a quality concern associated with tumorigencity. However, no simple in vitro me...

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Bibliografiska uppgifter
Huvudupphovsmän: Tano, Keiko, Yasuda, Satoshi, Kuroda, Takuya, Saito, Hirohisa, Umezawa, Akihiro, Sato, Yoji
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210199/
https://ncbi.nlm.nih.gov/pubmed/25347300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110496
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