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A Novel In Vitro Method for Detecting Undifferentiated Human Pluripotent Stem Cells as Impurities in Cell Therapy Products Using a Highly Efficient Culture System

Innovative applications of cell therapy products (CTPs) derived from human pluripotent stem cells (hPSCs) in regenerative medicine are currently being developed. The presence of residual undifferentiated hPSCs in CTPs is a quality concern associated with tumorigencity. However, no simple in vitro me...

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Bibliografiske detaljer
Main Authors: Tano, Keiko, Yasuda, Satoshi, Kuroda, Takuya, Saito, Hirohisa, Umezawa, Akihiro, Sato, Yoji
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210199/
https://ncbi.nlm.nih.gov/pubmed/25347300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110496
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