Expression of Truncated PITX3 in the Developing Lens Leads to Microphthalmia and Aphakia in Mice

Microphthalmia is a severe ocular disorder, and this condition is typically caused by mutations in transcription factors that are involved in eye development. Mice carrying mutations in these transcription factors would be useful tools for defining the mechanisms underlying developmental eye disorde...

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Bibliografiske detaljer
Main Authors: Wada, Kenta, Matsushima, Yoshibumi, Tada, Tomoki, Hasegawa, Sayaka, Obara, Yo, Yoshizawa, Yasuhiro, Takahashi, Gou, Hiai, Hiroshi, Shimanuki, Midori, Suzuki, Sari, Saitou, Junichi, Yamamoto, Naoki, Ichikawa, Masumi, Watanabe, Kei, Kikkawa, Yoshiaki
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210183/
https://ncbi.nlm.nih.gov/pubmed/25347445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111432
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