Expression of Truncated PITX3 in the Developing Lens Leads to Microphthalmia and Aphakia in Mice

Microphthalmia is a severe ocular disorder, and this condition is typically caused by mutations in transcription factors that are involved in eye development. Mice carrying mutations in these transcription factors would be useful tools for defining the mechanisms underlying developmental eye disorde...

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Detalhes bibliográficos
Main Authors: Wada, Kenta, Matsushima, Yoshibumi, Tada, Tomoki, Hasegawa, Sayaka, Obara, Yo, Yoshizawa, Yasuhiro, Takahashi, Gou, Hiai, Hiroshi, Shimanuki, Midori, Suzuki, Sari, Saitou, Junichi, Yamamoto, Naoki, Ichikawa, Masumi, Watanabe, Kei, Kikkawa, Yoshiaki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210183/
https://ncbi.nlm.nih.gov/pubmed/25347445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111432
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