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Microphthalmia in Texel Sheep Is Associated with a Missense Mutation in the Paired-Like Homeodomain 3 (PITX3) Gene

Microphthalmia in sheep is an autosomal recessive inherited congenital anomaly found within the Texel breed. It is characterized by extremely small or absent eyes and affected lambs are absolutely blind. For the first time, we use a genome-wide ovine SNP array for positional cloning of a Mendelian t...

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Detalhes bibliográficos
Main Authors: Becker, Doreen, Tetens, Jens, Brunner, Adrian, Bürstel, Daniela, Ganter, Martin, Kijas, James, Drögemüller, Cord
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805710/
https://ncbi.nlm.nih.gov/pubmed/20084168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008689
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