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Modular, Multi-Input Transcriptional Logic Gating with Orthogonal LacI/GalR Family Chimeras

[Image: see text] In prokaryotes, the construction of synthetic, multi-input promoters is constrained by the number of transcription factors that can simultaneously regulate a single promoter. This fundamental engineering constraint is an obstacle to synthetic biologists because it limits the comput...

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Autori principali: Shis, David L., Hussain, Faiza, Meinhardt, Sarah, Swint-Kruse, Liskin, Bennett, Matthew R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210161/
https://ncbi.nlm.nih.gov/pubmed/25035932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/sb500262f
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