AlloRep: a repository of sequence, structural and mutagenesis data for the LacI/GalR transcription regulators

Protein families evolve functional variation by accumulating point-mutations at functionally-important amino acid positions. Homologs in the LacI/GalR family of transcription regulators have evolved to bind diverse DNA sequences and allosteric regulatory molecules. In addition to playing key roles i...

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Pubblicato in:J Mol Biol
Autori principali: Sousa, Filipa L., Parente, Daniel J., Shis, David L., Hessman, Jacob A., Chazelle, Allen, Bennett, Matthew R., Teichmann, Sarah A., Swint-Kruse, Liskin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783282/
https://ncbi.nlm.nih.gov/pubmed/26410588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.09.015
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