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Multiple Co-Evolutionary Networks Are Supported by the Common Tertiary Scaffold of the LacI/GalR Proteins

Protein families might evolve paralogous functions on their common tertiary scaffold in two ways. First, the locations of functionally-important sites might be “hard-wired” into the structure, with novel functions evolved by altering the amino acid (e.g. Ala vs Ser) at these positions. Alternatively...

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Bibliografski detalji
Glavni autori: Parente, Daniel J., Swint-Kruse, Liskin
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877293/
https://ncbi.nlm.nih.gov/pubmed/24391951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084398
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