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Multiple Co-Evolutionary Networks Are Supported by the Common Tertiary Scaffold of the LacI/GalR Proteins
Protein families might evolve paralogous functions on their common tertiary scaffold in two ways. First, the locations of functionally-important sites might be “hard-wired” into the structure, with novel functions evolved by altering the amino acid (e.g. Ala vs Ser) at these positions. Alternatively...
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| Format: | Artigo |
| Sprache: | Inglês |
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Public Library of Science
2013
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3877293/ https://ncbi.nlm.nih.gov/pubmed/24391951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084398 |
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