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Detection of Lipid-Linked Peptidoglycan Precursors by Exploiting an Unexpected Transpeptidase Reaction
[Image: see text] Penicillin-binding proteins (PBPs) are involved in the synthesis and remodeling of bacterial peptidoglycan (PG). Staphylococcus aureus expresses four PBPs. Genetic studies in S. aureus have implicated PBP4 in the formation of highly cross-linked PG, but biochemical studies have not...
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Hauptverfasser: | , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
American Chemical
Society
2014
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4210121/ https://ncbi.nlm.nih.gov/pubmed/25291014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja508147s |
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