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Transpeptidase-mediated incorporation of D-Amino Acids into bacterial peptidoglycan

The beta-lactams are the most important class of antibiotics in clinical use. Their lethal targets are the transpeptidase domains of penicillin binding proteins (PBPs), which catalyze the crosslinking of bacterial peptidoglycan (PG) during cell wall synthesis. The transpeptidation reaction occurs in...

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Hlavní autoři: Lupoli, Tania J., Tsukamoto, Hirokazu, Doud, Emma H., Wang, Tsung-Shing Andrew, Walker, Suzanne, Kahne, Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172152/
https://ncbi.nlm.nih.gov/pubmed/21682301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2040656
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