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Transpeptidase-mediated incorporation of D-Amino Acids into bacterial peptidoglycan

The beta-lactams are the most important class of antibiotics in clinical use. Their lethal targets are the transpeptidase domains of penicillin binding proteins (PBPs), which catalyze the crosslinking of bacterial peptidoglycan (PG) during cell wall synthesis. The transpeptidation reaction occurs in...

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Detalhes bibliográficos
Main Authors: Lupoli, Tania J., Tsukamoto, Hirokazu, Doud, Emma H., Wang, Tsung-Shing Andrew, Walker, Suzanne, Kahne, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172152/
https://ncbi.nlm.nih.gov/pubmed/21682301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2040656
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