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Structural insights into the role of iron–histidine bond cleavage in nitric oxide-induced activation of H-NOX gas sensor proteins

Heme-nitric oxide/oxygen (H-NOX) binding domains are a recently discovered family of heme-based gas sensor proteins that are conserved across eukaryotes and bacteria. Nitric oxide (NO) binding to the heme cofactor of H-NOX proteins has been implicated as a regulatory mechanism for processes ranging...

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Autori principali: Herzik, Mark A., Jonnalagadda, Rohan, Kuriyan, John, Marletta, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210026/
https://ncbi.nlm.nih.gov/pubmed/25253889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416936111
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