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Structural insights into the molecular mechanism of H-NOX activation
Nitric oxide (NO) signaling in mammals controls important processes such as smooth muscle relaxation and neurotransmission by the activation of soluble guanylate cyclase (sGC). NO binding to the heme domain of sGC leads to dissociation of the iron–histidine (Fe–His) bond, which is required for enzym...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867026/ https://ncbi.nlm.nih.gov/pubmed/20162612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.357 |
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