Structural insights into the mechanism of oxidative activation of heme-free H-NOX from Vibrio cholerae

Bacterial heme nitric oxide/oxygen (H-NOX) domains are nitric oxide (NO) or oxygen sensors. This activity is mediated through binding of the ligand to a heme cofactor. However, H-NOX from Vibrio cholerae (Vc H-NOX) can be easily purified in a heme-free state that is capable of reversibly responding...

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Bibliografiska uppgifter
I publikationen:Biochem J
Huvudupphovsmän: Mukhopadhyay, Roma, Chacón, Kelly N., Jarvis, Jacqueline M., Talipov, Marat R., Yukl, Erik T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Portland Press Ltd. 2020
Ämnen:
Signaling
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108781/
https://ncbi.nlm.nih.gov/pubmed/32141496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20200124
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