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Characterization of Oxygen-Induced Retinopathy in Mice Carrying an Inactivating Point Mutation in the Catalytic Site of ADAM15

PURPOSE. Retinal neovascularization is found in diseases such as macular degeneration, diabetic retinopathy, or retinopathy of prematurity and is usually caused by alterations in oxygen supply. We have previously described that mice lacking the membrane-anchored metalloproteinase ADAM15 (a Disintegr...

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Main Authors: Maretzky, Thorsten, Blobel, Carl P., Guaiquil, Victor
Formato: Artigo
Idioma:Inglês
Publicado: The Association for Research in Vision and Ophthalmology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209716/
https://ncbi.nlm.nih.gov/pubmed/25249606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14472
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