Cutting the brakes and flooring the gas: how TMEPAI turns TGF-β into a tumor promoter

In normal or nonmalignant cells, TGF-β inhibits cellular proliferation through activation of the SMAD-dependent canonical signaling pathway. Recent findings demonstrate that the protein TMEPAI1 can block the cytostatic effects of the canonical TGF-β signaling pathway, while activating cellular proli...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cichon, Magdalena A., Radisky, Derek C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2014
Gaiak:
Research Perspective
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209605/
https://ncbi.nlm.nih.gov/pubmed/25352947
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