Substantial Effect of Efavirenz Monotherapy on Bilirubin Levels in Healthy Volunteers

BACKGROUND: Efavirenz exhibits multiple interactions with drug-metabolizing enzymes and transporters, and for this reason efavirenz-based HIV therapy is associated with altered pharmacokinetics of coadministered drugs. Probably by the same mechanism, efavirenz-based HIV therapy affects the dispositi...

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Main Authors: Metzger, Ingrid F., Quigg, Troy C., Epstein, Noam, Aregbe, Abdulateef O., Thong, Nancy, Callaghan, John T., Flockhart, David A., Nguyen, Anne T., Stevens, Colleen K., Gupta, Samir K., Desta, Zeruesenay
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2014
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209507/
https://ncbi.nlm.nih.gov/pubmed/25352936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.curtheres.2014.05.002
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