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DNA-based digital tension probes reveal integrin forces during early cell adhesion

Mechanical stimuli profoundly alter cell fate, yet the mechanisms underlying mechanotransduction remain obscure due to a lack of methods for molecular force imaging. Here, to address this need, we develop a new class of molecular tension probes that function as a switch to generate a 20–30-fold incr...

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Detalhes bibliográficos
Main Authors: Zhang, Yun, Ge, Chenghao, Zhu, Cheng, Salaita, Khalid
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209443/
https://ncbi.nlm.nih.gov/pubmed/25342432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6167
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