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Nanoparticle Tension Probes Patterned at the Nanoscale: Impact of Integrin Clustering on Force Transmission

[Image: see text] Herein we aimed to understand how nanoscale clustering of RGD ligands alters the mechano-regulation of their integrin receptors. We combined molecular tension fluorescence microscopy with block copolymer micelle nanolithography to fabricate substrates with arrays of precisely space...

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Detalhes bibliográficos
Main Authors: Liu, Yang, Medda, Rebecca, Liu, Zheng, Galior, Kornelia, Yehl, Kevin, Spatz, Joachim P., Cavalcanti-Adam, Elisabetta Ada, Salaita, Khalid
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189618/
https://ncbi.nlm.nih.gov/pubmed/25238229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl501912g
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