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DNA-based digital tension probes reveal integrin forces during early cell adhesion
Mechanical stimuli profoundly alter cell fate, yet the mechanisms underlying mechanotransduction remain obscure due to a lack of methods for molecular force imaging. Here, to address this need, we develop a new class of molecular tension probes that function as a switch to generate a 20–30-fold incr...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4209443/ https://ncbi.nlm.nih.gov/pubmed/25342432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6167 |
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