Glucocorticoids Induce Cardiac Fibrosis via Mineralocorticoid Receptor in Oxidative Stress: Contribution of Elongation Factor Eleven-Nineteen Lysine-Rich Leukemia (ELL)

BACKGROUND: Cardiac fibrosis is considered to be a crucial factor in the development of heart failure. Blockade of the mineralocorticoid receptor (MR) attenuated cardiac fibrosis and improved the prognosis of patients with chronic heart failure but the ligand for MR and the regulatory mechanism of M...

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Hlavní autoři: Omori, Yosuke, Mano, Toshiaki, Ohtani, Tomohito, Sakata, Yasushi, Takeda, Yasuharu, Tamaki, Shunsuke, Tsukamoto, Yasumasa, Miwa, Takeshi, Yamamoto, Kazuhiro, Komuro, Issei
Médium: Artigo
Jazyk:Inglês
Vydáno: Tottori University Faculty of Medicine 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4209341/
https://ncbi.nlm.nih.gov/pubmed/25349466
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