Interleukin-16 Promotes Cardiac Fibrosis and Myocardial Stiffening in Heart Failure with Preserved Ejection Fraction

BACKGROUND: Chronic heart failure (CHF) with preserved left ventricular (LV) ejection fraction (HFpEF) is observed in half of all patients with CHF and carries the same poor prognosis as CHF with reduced LV ejection fraction (HFrEF). In contrast to HFrEF, there is no established therapy for HFpEF. C...

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Detalhes bibliográficos
Main Authors: Tamaki, Shunsuke, Mano, Toshiaki, Sakata, Yasushi, Ohtani, Tomohito, Takeda, Yasuharu, Kamimura, Daisuke, Omori, Yosuke, Tsukamoto, Yasumasa, Ikeya, Yukitoshi, Kawai, Mari, Kumanogoh, Atsushi, Hagihara, Keisuke, Ishii, Ryohei, Higashimori, Mitsuru, Kaneko, Makoto, Hasuwa, Hidetoshi, Miwa, Takeshi, Yamamoto, Kazuhiro, Komuro, Issei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716890/
https://ncbi.nlm.nih.gov/pubmed/23894370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068893
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