The Eleven-Nineteen Lysine-rich Leukemia Gene (ELL2) Influences the Histone H3 Protein Modifications Accompanying the Shift to Secretory Immunoglobulin Heavy Chain mRNA Production

In plasma cells, immunoglobulin heavy chain (IgH) secretory-specific mRNA is made in high abundance as a result of both increased promoter proximal poly(A) site choice and weak splice-site skipping. Ell2, the eleven-nineteen lysine rich leukemia gene, is a transcription elongation factor that is ind...

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Bibliographic Details
Main Authors: Milcarek, Christine, Albring, Michael, Langer, Creityeka, Park, Kyung Soo
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190787/
https://ncbi.nlm.nih.gov/pubmed/21832080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.272096
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