Characterization of a weakly expressed KIR2DL1 variant reveals a novel upstream promoter that controls KIR expression

Members of the human KIR class I MHC receptor gene family contain multiple promoters that determine the variegated expression of KIR on NK cells. In order to identify novel genetic alterations associated with decreased KIR expression, a group of donors was characterized for KIR gene content, transcr...

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Detalhes bibliográficos
Main Authors: Wright, Paul W., Li, Hongchuan, Huehn, Andrew, O’Connor, Geraldine M, Cooley, Sarah, Miller, Jeffrey S., Anderson, Stephen K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208966/
https://ncbi.nlm.nih.gov/pubmed/24989671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2014.34
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