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Characterization of KIR intermediate promoters reveals four promoter types associated with distinct expression patterns of KIR subtypes

The human KIR genes contain multiple promoters that control the process of gene activation and variegated expression of KIR on NK and T cells. Specific subfamilies of KIR genes have differences in the timing and tissue-specificity of expression: however, previous studies of the proximal KIR promoter...

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Pubblicato in:Genes Immun
Autori principali: Li, Hongchuan, Wright, Paul W., McCullen, Matthew, Anderson, Stephen K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724278/
https://ncbi.nlm.nih.gov/pubmed/26656451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2015.56
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