Genetic Control of Variegated KIR Gene Expression: Polymorphisms of the Bi-Directional KIR3DL1 Promoter Are Associated with Distinct Frequencies of Gene Expression

Natural killer (NK) cells play an important role in the detection and elimination of tumors and virus-infected cells by the innate immune system. Human NK cells use cell surface receptors (KIR) for class I MHC to sense alterations of class I on potential target cells. Individual NK cells only expres...

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Bibliografiska uppgifter
Huvudupphovsmän: Li, Hongchuan, Pascal, Véronique, Martin, Maureen P., Carrington, Mary, Anderson, Stephen K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2008
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575236/
https://ncbi.nlm.nih.gov/pubmed/19008943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000254
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