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SGLT2 inhibitors act from the extracellular surface of the cell membrane

SGLT2 inhibitors are a new class of drugs that have been recently developed to treat type II diabetes. They lower glucose levels by inhibiting the renal Na(+)/glucose cotransporter SGLT2, thereby increasing the amount of glucose excreted in the urine. Pharmacodynamics studies have raised questions a...

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Bibliographic Details
Main Authors: Ghezzi, Chiara, Hirayama, Bruce A., Gorraitz, Edurne, Loo, Donald D. F., Liang, Yin, Wright, Ernest M.
Format: Artigo
Language:Inglês
Published: Wiley Periodicals, Inc. 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208661/
https://ncbi.nlm.nih.gov/pubmed/24973332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12058
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