Glucose transport by human renal Na(+)/d-glucose cotransporters SGLT1 and SGLT2

The human Na(+)/d-glucose cotransporter 2 (hSGLT2) is believed to be responsible for the bulk of glucose reabsorption in the kidney proximal convoluted tubule. Since blocking reabsorption increases urinary glucose excretion, hSGLT2 has become a novel drug target for Type 2 diabetes treatment. Glucos...

Full description

Saved in:
Bibliographic Details
Main Authors: Hummel, Charles S., Lu, Chuan, Loo, Donald D. F., Hirayama, Bruce A., Voss, Andrew A., Wright, Ernest M.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2011
Subjects:
Membrane Transporters, Ion Channels and Pumps
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023189/
https://ncbi.nlm.nih.gov/pubmed/20980548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00388.2010
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items