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Functional identification and characterization of sodium binding sites in Na symporters

Sodium cotransporters from several different gene families belong to the leucine transporter (LeuT) structural family. Although the identification of Na(+) in binding sites is beyond the resolution of the structures, two Na(+) binding sites (Na1 and Na2) have been proposed in LeuT. Na2 is conserved...

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Bibliografiska uppgifter
Huvudupphovsmän: Loo, Donald D. F., Jiang, Xuan, Gorraitz, Edurne, Hirayama, Bruce A., Wright, Ernest M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839715/
https://ncbi.nlm.nih.gov/pubmed/24191006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319218110
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