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Probing murine methyltransfease Dnmt3a interactions with benzo[a]pyrene-modified DNA by fluorescence methods

The impact of bulky carcinogen-DNA adducts positioned at or near recognition sites (CpG) of eukaryotic DNA methyltransferases on their catalytic activities is poorly understood. In this work we have employed site-specifically modified 30-mer oligodeoxyribonucleotides containing stereoisomeric benzo[...

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Bibliografische gegevens
Hoofdauteurs: Minero, Antonio S., Lukashevich, Olga V., Cherepanova, Natalia A., Kolbanovskiy, Alexander, Geacintov, Nicholas E., Gromova, Elizaveta S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208501/
https://ncbi.nlm.nih.gov/pubmed/22913541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2012.08756.x
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