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Dnmt3a-CD is Less Susceptible to Bulky Benzo[a]pyrene diol epoxide-derived DNA Lesions than Prokaryotic DNA Methyltransferases
Benzo[a]pyrene (B[a]P) is a well-characterized environmental polycyclic aromatic hydrocarbon pollutant. In living organisms, B[a]P is metabolized to the genotoxic anti-benzo[a]pyrene diol epoxide that reacts with cellular DNA to form stereoisomeric anti-B[a]PDE-N(2)-dG adducts. In this study, we exp...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076715/ https://ncbi.nlm.nih.gov/pubmed/21174446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101717b |
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