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Acetylcholine and antibodies against the acetylcholine receptor protect neurons and astrocytes against beta-amyloid toxicity

Aggregated amyloid-β causes pathological changes in mixed cultures of neurons and astrocytes such as sporadic cytoplasmic intracellular Ca(2+)-signalling, increase in reactive oxygen species production and cell death. Some of the toxic effects of amyloid-β are mediated through the interaction of the...

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Bibliografiske detaljer
Main Authors: Kamynina, Anna V., Holmström, Kira M., Koroev, Dmitriy O., Volpina, Olga M., Abramov, Andrey Y.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208291/
https://ncbi.nlm.nih.gov/pubmed/23353645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2013.01.011
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