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Stress-enhanced translation of γ-globin mRNA

In this issue of Blood, Hahn and Lowrey demonstrate enhanced translation of γ-globin messenger RNA (mRNA) upon activation of eukaryotic initiation factor 2αP (eIF2αP) stress signaling. This finding underscores translational control as a novel mechanism in regulating fetal hemoglobin production (HbF)...

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Autor principal: Chen, Jane-Jane
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208276/
https://ncbi.nlm.nih.gov/pubmed/25342665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-09-599290
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