Quercetin-3-glucoside increases low-density lipoprotein receptor (LDLR) expression, attenuates proprotein convertase subtilisin/kexin 9 (PCSK9) secretion, and stimulates LDL uptake by Huh7 human hepatocytes in culture

Low-density lipoprotein receptor (LDLR) mediates hepatic clearance of plasma cholesterol; proprotein convertase subtilisin/kexin 9 (PCSK9) opposes this clearance by promoting LDLR degradation. The plant flavonoid quercetin-3-β-d-glucoside (Q3G) has been shown to reduce hypercholesterolemia in experi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mbikay, Majambu, Sirois, Francine, Simoes, Sonia, Mayne, Janice, Chrétien, Michel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208090/
https://ncbi.nlm.nih.gov/pubmed/25349780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2014.08.003
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak