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Molecular and cellular function of the proprotein convertase subtilisin/kexin type 9 (PCSK9)

The proprotein convertase subtilisin/kexin type 9 (PCSK9) has emerged as a promising treatment target to lower serum cholesterol, a major risk factor of cardiovascular diseases. Gain-of-function mutations of PCSK9 are associated with hypercholesterolemia and increased risk of cardiovascular events....

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Detalhes bibliográficos
Publicado no:Basic Res Cardiol
Main Authors: Schulz, Rainer, Schlüter, Klaus-Dieter, Laufs, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298671/
https://ncbi.nlm.nih.gov/pubmed/25600226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-015-0463-z
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