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Molecular and cellular function of the proprotein convertase subtilisin/kexin type 9 (PCSK9)
The proprotein convertase subtilisin/kexin type 9 (PCSK9) has emerged as a promising treatment target to lower serum cholesterol, a major risk factor of cardiovascular diseases. Gain-of-function mutations of PCSK9 are associated with hypercholesterolemia and increased risk of cardiovascular events....
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| Publié dans: | Basic Res Cardiol |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer Berlin Heidelberg
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4298671/ https://ncbi.nlm.nih.gov/pubmed/25600226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-015-0463-z |
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