MicroRNA-539 Is Up-regulated in Failing Heart, and Suppresses O-GlcNAcase Expression

Derangements in metabolism and related signaling pathways characterize the failing heart. One such signal, O-linked β-N-acetylglucosamine (O-GlcNAc), is an essential post-translational modification regulated by two enzymes, O-GlcNAc transferase and O-GlcNAcase (OGA), which modulate the function of m...

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Detalhes bibliográficos
Main Authors: Muthusamy, Senthilkumar, DeMartino, Angelica M., Watson, Lewis J., Brittian, Kenneth R., Zafir, Ayesha, Dassanayaka, Sujith, Hong, Kyung U., Jones, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207981/
https://ncbi.nlm.nih.gov/pubmed/25183011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.578682
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