Nilotinib Is More Potent than Imatinib for Treating Plexiform Neurofibroma In Vitro and In Vivo

Plexiform neurofibromas (PNFs) are benign nerve sheath tumors mostly associated with neurofibromatosis type 1. They often extend through multiple layers of tissue and therefore cannot be treated satisfactorily by surgery. Nilotinib is a tyrosine kinase inhibitor used to treat leukemia, with advantag...

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Detaylı Bibliyografya
Asıl Yazarlar: Wei, Jiang, Freytag, Marcus, Schober, Yvonne, Nockher, Wolfgang A., Mautner, Victor F., Friedrich, Reinhard E., Manley, Paul W., Kluwe, Lan, Kurtz, Andreas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207688/
https://ncbi.nlm.nih.gov/pubmed/25340526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107760
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