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Non-coding RNA ANRIL and the number of plexiform neurofibromas in patients with NF1 microdeletions

BACKGROUND: Neurofibromatosis type-1 (NF1) is caused by mutations of the NF1 gene at 17q11.2. In 95% of non-founder NF1 patients, NF1 mutations are identifiable by means of a comprehensive mutation analysis. 5-10% of these patients harbour microdeletions encompassing the NF1 gene and its flanking re...

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Autors principals: Mußotter, Tanja, Kluwe, Lan, Högel, Josef, Nguyen, Rosa, Cooper, David N, Mautner, Victor-Felix, Kehrer-Sawatzki, Hildegard
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500256/
https://ncbi.nlm.nih.gov/pubmed/23101500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-13-98
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